H 36 pill finasteride (Propecia, Amethard, Janssen, USA) 1 × 10 8 - mg/d 3 wk PRA, SC-FFQ, HRSD at baseline and 12 wk of treatment with or without 0.1 mg/d finasteride, 4.2 bicalutamide, and 2.5 mg/d raloxifene; baseline 12 wk of treatment and maintenance with bicalutamide (data not shown). ANOVA with multiple treatment sessions included only finasteride and bicalutamide. Citalopram, dothiepin, duloxetine were not administered in any of the three trials. †Citalopram was administered for treatment purposes as an antiarrhythmic drug (CIS No. 015-18, Becton Dickinson, Boston, MA) in one trial; however, it was not administered during the second or third week of study. ‡Sustained-release Citalopram for therapy purposes [not applicable to all studies] was administered with finasteride in one trial only. §There were no statistically significant differences according to therapy assignment. evaluate whether the finasteride effects would last beyond the 12-month followup assessment, effects of finasteride administration on HRSD, as measured by the primary outcome of trial, were analyzed for the full 12-month followup and for the first 1, 2, and 4 weeks of the 6-month and 12-month followup assessments, respectively. As noted above, treatment with finasteride may be associated a reduction in HRSD scores over the 6-month followup, but not through the 12-month followup assessment because of other treatment-related adverse effects [see Clinical Studies (14.1)]. Table 2. Change in HRSD at 1, 2, 3, and 6 Months in 6- 12-Month Posttreatment and Maintenance Treatment Arm (n = 773) Group 1 723) 2 (n = 750) Group 3 737) Change from Baseline to All Times Points (mean ± SD) online coupons canada drug pharmacy 1.6 1.9 –0.4 1.4 ± 1.1 0.2 1.0 0.7 1.5 –9.4 ± 15.5 % Total Subjects, %a 37.2±7.5 56.3±12.5 35.1±6.9 41.8±8.8 53.2±14.2 –2.1±9.8 –9.0 ± 18.8 % Body Mass Indexc, %b 27.5±3.9 27.0±4.1 26.5±3.4 27.8±3.7 26.4±4.1 0.2±1.4 0.0 ± 4.7 Body Mass Index Mean (SD), % 27.7 (0.2) 29.5 (0.9) 28.3 (1.3) 29.9 (1.4) 28.2 (0.9) –1.4±7.1 0.0 ± 6.2 Body Sizes Mean Finast 5mg $261.89 - $2.18 Per pill (SD), %b 33.2 (1.5) 33.0 (1.4) 32.8 (1.7) (0.9) 0.1±3.6 0.0 ± 3.9 Body Weight, kg Mean (SD), %b 80.0 (12.9) 78.1 (10.6) 80.7 (12.2) 80.9 (10.9) 79.9 (14.8) –5.8±8.3 0.1 ± 7.2 Change in HRSD at 1, 2, 3, and 6 Months in 6- 12-Month Posttreatment and Maintenance Treatment Arm (n = 773) Group 1 723) 2 (n = 750) Group 3 737) Change from Baseline to All Times Points (mean ± SD) 1.6 1.9 –0.
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